The British Journal of Clinical Pharmacy
– Volume 1, Issue 4 April 2009

EDITOR'S COMMENTS
  Embracing Leadership
   
NEWS
  Concerns raised over the draft Pharmacy Order 2009
  Early antiretroviral therapy improves survival
  Cetuximab efficacy in colorectal cancer affected by KRAS gene



   
NEWS FEATURE
  Pharmacy enters Second Life
The European Association of Hospital Pharmacists (EAHP) is the latest pharmacy organisation to take the plunge into the virtual world Second Life. Shona Kirk pays them a visit and investigates progress with other virtual pharmacy projects.
 
CLINICAL UPDATES
Eculizumab: pharmacology and clinical effectiveness
Patient access to eculizumab, a monoclonal antibody used for the treatment of paroxysmal nocturnal haemoglobinuria, may be more transparent following new arrangements for central commissioning. Simon Keady, Simon Cheesman and Richard Kelly outline the drug’s pharmacology and evidence for use.
New national funding for the management of PNH
This April saw the start of a new central funding pathway for the monoclonal antibody eculizumab, for the treatment of patients with paroxysmal nocturnal haemoglobinuria. In this article, staff from St James' Hospital, Leeds and University College London Hospital describe how the new service will work.
   
LETTERS
  Readers’ letters
Promote leadership - Ann Lewis, visiting professor, University of London School of Pharmacy.
Clear definition needed - Chris Barrett, retired pharmacist - former chief pharmacist at Barts and the London NHS Trust.
   
OPINION
 

Clinical leadership required — and that means you!
Martin Stephens explains the importance of clinical leadership in improving patient care, and why this refers to pharmacists at all levels of practice.

Professional body debate is heading off at a tangent
Much debate surrounding the establishment of the new professional body for pharmacy seems to be missing the point. Rather than becoming preoccupied with restricted titles, we need to concentrate on sector-wide collaboration to provide the best clinical care to patients, says Philip Brown.

   
MEETINGS
 

Pharmacists should recognise the need for genetic testing
Personalising medicines according to a patient’s genetic makeup is becoming easier with increasing knowledge and commercially available tests, yet it is not routinely used in clinical practice. Attendees at the EAHP congress heard why pharmacists should help advocate such tests. By Hannah Pike.

   
PRESCRIBER'S CORNER
  Management of RA in a patient intolerant to therapy

Prescriber's Corner describes situations encountered by pharmacist prescribers and invites you to consider clinical decisions about the patient. In this case, you are managing a patient with rheumatoid arthritis who is either intolerant of, or unresponsive to, standard drug treatment.

   
SHARING PRACTICE
 

Changing catheter-locking solutions to reduce infection
Trisodium citrate has recently been introduced as a catheter-locking solution in Addenbrooke's Hospital, Cambridge. Jo Jenkins, Clare Daniels and Nick Pritchard describe the impact this has had on reducing catheter-related infections in patients receiving haemodialysis.

Improving patient counselling in capecitabine treatment
Outpatients taking oral chemotherapy need careful counselling. Reshenthie Govender describes the early benefits from a pilot study to establish a standard counselling procedure and improve the experience for patients taking capecitabine at a specialist oncology centre.

Raising prescribing standards through doctor training
Involving clinical pharmacists in the training programme for junior doctors can be beneficial for both the doctors and the pharmacy department. Alyson Williamson describes the approach taken by one trust and the feedback received to date.

   
The British Journal of Clinical Pharmacy is an editorially independent publication.
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